Vol. 9, Issue 2, Part A (2023)

Abstract
The aim of the study was to screen the antibacterial activity and phytochemical analysis of various extracts of Celsia coromandeliana a member of Scrophulariaceae family. The antibacterial activity of various extracts of Celsia coromandeliana was determined with agar-well diffusion method. The results provide evidence that the extracts of Celsia coromandeliana contained glycosides, flavonoids, saponins and phenolic compounds which may be responsible for the substantial antibacterial activity. Among different solvent extract, chloroform and n-butanol extracts exhibited a broad spectrum of antimicrobial activity. It showed strong antibacterial activity against Gram positive bacterial strain like Klebsiella pneumoniae, Bacillus subtilis and Gram negative strains like Escherichia coli. The ethanolic and ethyl acetate extract showed low antibacterial activity against the bacterial strains. The study ascertains the value of plants used in Ayurveda, which could be of considerable interest to the development of new drugs, to supports there is scientific basis of their utilization in traditional medicinal for wound healing and also in treatment of some infectious diseases.