Vol. 1, Issue 1, Part F (2014)

Introduction: Hypothyroidism is known to affect various organ systems, including the kidneys. This study aimed to assess the impact of hypothyroidism on renal function tests and serum electrolyte levels.

Material and Methods: A hospital-based case-control study was conducted at Mamata Medical College, Department of Biochemistry. The study included 50 participants, divided into 25 hypothyroid patients and 25 euthyroid controls. Renal function tests (serum creatinine, blood urea nitrogen) and serum electrolyte levels (sodium, potassium, calcium, phosphorus) were measured, along with thyroid function tests (TSH, T4, T3).

Results: Hypothyroid patients exhibited significantly higher serum creatinine and blood urea nitrogen levels compared to euthyroid controls, indicating impaired renal function. Serum sodium and calcium levels were also significantly lower in the hypothyroid group, while potassium and phosphorus levels showed no significant difference. Thyroid function tests confirmed the diagnosis of hypothyroidism in the patient group.

Conclusion: The study highlights the significant impact of hypothyroidism on renal function and electrolyte balance. Regular monitoring of these parameters is essential in hypothyroid patients for early detection and management of potential complications. Further research with larger samples is needed to fully understand the systemic effects of hypothyroidism.