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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

IMPACT FACTOR (RJIF): 8.4

Vol. 1, Issue 1, Part F (2014)

A randomized controlled trial examining clobazam vs. intermittent oral levetiracetam for the prevention of febrile seizures in children

A randomized controlled trial examining clobazam vs. intermittent oral levetiracetam for the prevention of febrile seizures in children

Author(s)
Dr. S Satyanarayanan and Dr. Kolati Naveen
Abstract
Introduction: A simple febrile seizure is defined as a generalized seizure lasting less than fifteen minutes in a child between the ages of six months and five years, that does not repeat within twenty-four hours, and that is not preceded by or associated with an acute neurological illness. The most prevalent form of epilepsy in children is febrile seizures.
Methods: Children examined at an outpatient pediatric clinic who have experienced febrile seizures in the past. The identity of this randomized controlled experiment was disclosed to the participants. From January 2013 to December 2013, the study was conducted at the pediatric department at Madha Medical College and Research Institute in Chennai, India. Using simplified random sampling, the study participants were selected. The computer will do the randomization procedure.
Results: Children with a history of febrile seizures, defined as two or more episodes of febrile seizures in the preceding six months and at least one seizure recurrence in the preceding two weeks, ranging in age from six months to five years, were the subjects. This study's main goals are to assess the efficacy of oral levetiracetam and clobazam in treating febrile seizures in children and to ascertain how frequently these seizures recur following a 48-week follow-up period.
Conclusion: The study discovered that levetiracetam was much more beneficial than clobazam in lowering the frequency of recurrent febrile seizures, despite the effectiveness of both medications in this regard.
Pages: 590-593  |  68 Views  28 Downloads


International Journal of Applied Research
How to cite this article:
Dr. S Satyanarayanan, Dr. Kolati Naveen. A randomized controlled trial examining clobazam vs. intermittent oral levetiracetam for the prevention of febrile seizures in children. Int J Appl Res 2014;1(1):590-593.
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